白塞病发病机制及治疗研究进展

Research Advances in Pathogenesis and Treatment of Behcet′s Disease

白塞病(Behcet’s disease,BD)是一种多系统参与的血管炎性疾病。患者在人口特征、器官表现、复发频率和程度、病程、治疗反应以及预后方面存在着巨大差异,这种异质性使得对病情严重程度评估、管理策略变得困难。近年来,在BD的发病机制及治疗方面取得了新的发现,本文就近5年的研究进展作一综述。

Behcet′s disease(BD) is a variable vessel vasculitis with multi-system involvement that shows important heterogeneity among patients regarding demographic features, organ manifestations, frequency and severity of relapses, disease course, response to treatment and prognosis. This heterogeneity has made it difficult to standardize disease assessment and to develop management strategies. Several new studies have been published during the recent years exploring the pathogenesis and management of Behcet′s disease. The aim of this review is to provide an overview of the most relevant recent research in Behcet′s disease in the past 5 years.