子宫肌瘤卵巢囊肿在采用不同手术方法治疗后对女性内分泌及生理功能的影响

Effects of different surgical methods on female endocrine and physiological functions of uterine fibroids and ovarian cysts

目的探讨在子宫肌瘤卵巢囊肿患者的临床治疗中应用不同手术方法对患者内分泌与生理功能的影响。方法选择我院收治的子宫肌瘤卵巢囊肿患者86例,经双盲法分为两组,每组各43例。试验组接受腹腔镜手术治疗,对照组接受传统开腹手术治疗,比较不同手术治疗方法的手术情况(手术时长、术中出血量、术后出院时间)、对性功能指标影响[促卵泡生成激素(Follicle-stimulating Hormone,FSH)、促黄体生成激素(Luteinising Hormone,LH)、孕酮(Progesterone,P)、抗苗勒管激素(Anti-Mullerian?Hormone,AMH)]以及术后并发症发生率(切口感染、盆腔粘连)。结果试验组手术时间与住院时间均短于对照组,试验组术中出血量少于对照组(P<0.05),治疗后,两组LH、AMH、P水平均低于治疗前,试验组雌二醇(Estradiol,E2)低于治疗前,FSH水平高于治疗前,试验组FSH水平低于对照组,E2、LH、AMH、P水平高于对照组(P<0.05)。结论在子宫肌瘤卵巢囊肿患者的临床治疗中,应用腹腔镜手术的治疗效果高于传统开腹手术,可改善性激素水平,且术后并发症发生率较低,值得推广。

Objective To investigate the effects of different surgical methods on the endocrine and physiological functions of female patients with uterine fibroids and ovarian cysts.Methods Eighty-six patients with uterine fibroids and ovarian cysts in our hospital were selected and divided into two groups by double-blind method,with 43 cases in each group.The experimental group received laparoscopic surgery,and the control group received traditional open surgery.The operation conditions of different surgical treatment methods(operating time,intraoperative blood loss,postoperative discharge time)and the impact on sexual function indicators were compared(Follicle-stimulating Hormone,FSH),Luteinising Hormone(LH),Progesterone(P),Anti-Mullerian Hormone(AMH)and the incidence of postoperative complications(Incision infection,pelvic adhesions).Results The operation time and hospital stay in the experimental group were shorter than those in the control group.The blood loss during the operation in the experimental group was less than that in the control group(P<0.05).After treatment,the LH,AMH,and P levels in the two groups were lower than those before the treatment.Estradiol(E2)was lower than before treatment,FSH level was higher than before treatment,FSH level in test group was lower than than in the control group,E2,LH,AMH,and P levels were higher than control group(P<0.05).Conclusion In the clinical treatment of patients with uterine fibroids and ovarian cysts,the therapeutic effect of laparoscopic surgery is higher than that of traditional open surgery,it can improve the level of sex hormones,and the incidence of postoperative complications is lower,which is worthy of promotion.