探讨降钙素原(PCT)、超敏C反应蛋白(hs-CRP)及白细胞(WBC)水平在慢性阻塞性肺疾病(COPD)急性加重期(AECOPD)判定中的临床价值

To Investigate the Clinical Value of Calcitonin(PCT), High Sensitive C Reactive Protein(hs-CRP) and Leukocyte(WBC) Level in the Determination of(AECOPD) in Acute Exacerbation of(COPD) in Chronic Obstructive Pulmonary Disease(COPD)

目的分析慢性阻塞性肺疾病(COPD)急性加重期(AECOPD)判定中降钙素原(PCT)、超敏C反应蛋白(hs-CRP)及白细胞(WBC)应用价值。方法将2018年10月至2019年10月本院接收的400例AECOPD患者纳入至研究组中,将同期400例稳定期COPD患者纳入至对照组中,对比WBC、hsCRP及PCT水平,并统计hs-CRP及PCT阳性率,并比较AECOPD患者治疗前后WBC、hs-CRP及PCT水平。结果在WBC、hs-CRP及PCT方面,研究组均较对照组更高,差异有统计学意义(P<0.05);在hsCRP阳性率及PCT阳性率方面,研究组(40.00%,69.00%)较对照组(16.00%,24.00%)更高,差异有统计学意义(P<0.05)。结论血清hs-CRP及PCT在AECOPD诊断中具有较高的应用价值,通过对上述两项指标检测,能够对COPD疾病的发展及发生有效预测,从而予以患者有效治疗方法,促进治疗效果提高。

Objective To analyze the value of(AECOPD)in the determination of troponin(PCT),high sensitive C reactive protein(hs-CRP)and leukocyte(WBC)in patients with chronic obstructive pulmonary disease(COPD)in acute exacerbation of chronic obstructive pulmonary disease(COPD).Methods From October 2018 to October 2019,400 patients with AECOPD received by our hospital were included in the study group,and 400 patients with stable COPD in the same period were included in the control group.The levels of WBC,hs-CRP and PCT were compared,the positive rates of hs-CRP and PCT were counted,and the levels of WBC,hs-CRP and PCT in patients with AECOPD before and after treatment were compared.Results In terms of WBC,hs-CRP and PCT,the positive rate of hs-CRP and PCT in the study group was higher than that in the control group(P<0.05),and the positive rate of hs-CRP and PCT in the study group(16.00%,24.00%)was significantly higher than that in the control group(P<0.05).Conclusion The serum hs-CRP and PCT have high application value in the diagnosis of AECOPD,and can be used for effectively treating the development of the COPD and the occurrence of an effective prediction through the detection of the two indexes,so that the effective treatment method of the patient can be achieved,and the treatment effect is improved.