2019年太仓市食管癌发病和死亡情况及2010—2019年变化趋势分析

Incidence and mortality of esophageal cancer in Taicang in 2019 and its trends from 2010 to 2019

目的分析太仓市2019年食管癌的发病与死亡情况及2010—2019年变化趋势。方法食管癌发病数据来源于太仓市恶性肿瘤登记报告系统,死亡数据来源于死因登记系统。使用Excel 2019及SPSS 18.0软件计算粗发病率和病死率、中标发病率和病死率、世标发病率和病死率、0~74岁累积率、35~64岁截缩率,男女组间比较采用χ^(2)检验。通过Joinpoint软件计算年度变化百分比(annual percentage change,APC)及95%可信区间。结果2019年食管癌粗发病率为7.23/10万,中标率和世标率分别为2.24/10万和2.31/10万。粗病死率为7.84/10万,中标率和世标率分别为2.60/10万和2.62/10万。粗发病率和病死率、中标率、世标率、0~74岁累积率、35~64岁截缩率男性均高于女性;此外,历年发病和死亡男性也均高于女性(P<0.05);食管癌发病及死亡均呈下降趋势,其中粗发病率、中标发病率、世标发病率的APC分别为-3.94%、-9.76%、-9.37%(P<0.01),粗病死率、中标病死率、世标病死率的APC分别为-3.87%、-9.08%、-9.02%(P<0.01)。结论太仓市2019年食管癌发病及死亡低于全国及全省水平,近10年食管癌发病及死亡男性均高于女性,粗发病率和粗病死率,中标发病率和病死率、世标发病率和病死率均呈现下降趋势。

Objective To analyze the incidence and mortality of esophageal cancer in Taicang in 2019 and its trends from 2010 to 2019.Methods The cases of esophageal cancer came from the tumor registration and reporting system of Taicang,and the deaths came from the cause of death registration system.Crude incidence,crudemortality,incidence rate by Chinese standard population,incidence rate by world standard population,mortality rate by Chinese standard population,and mortality rate by world standard population,cumulative rate of 0-74 years,truncated rate of 35-64 years were calculated by Excel 2019 and SPSS 18.0.Chi-square test was used for comparison between men and women.Joinpoint software was used to calculate annual percentage change and 95%confidence interval.Results In 2019,the crude incidence of esophageal cancer was 7.23 per 100000,and the incidence rate by Chinese standard population and incidence rate by the world standard rate were 2.24 per 100000 and 2.31 per 100000,respectively.The crude mortality rate was 7.84 per 100000,and the mortality rate by Chinese standard population and mortality rate by the world standard population were 2.60 per 100000 and 2.62 per 100000 respectively.The crude morbidity and mortality,the morbidity and mortality rate by Chinese standard population,the morbidity and mortality rate by the world standard population,the accumulation rate of 0-74 years old and the truncation rate of 35-64 years old were all higher in males than in females.Between 2010 and 2019,morbidity and mortality of male were higher than that of female.The incidence and death of esophageal cancer showed a decreasing trend,and the APCs of crude incidence,incidence by Chinese standard population and incidence by the world standard population were-3.94%,-9.76%and-9.37%,respectively(P<0.01).The APCs of crude mortality,mortality by Chinese standard population and mortality by the world standard population were-3.87%,-9.08%and-9.02%,respectively(P<0.01).Conclusion The incidence and mortality of esophageal cancer in Taicang in 2019 were lower than the national level.In the past 10 years,the incidence and death of esophageal cancer in males were higher than that in females.Crude morbidity and crude mortality,morbidity and mortality by Chinese standard population,morbidity and mortality by world standard population all showed a decreasing trend.