腹膜透析相关性腹膜炎频发的危险因素分析

Risk factors of frequent peritoneal dialysis-related peritonitis

目的探讨腹膜透析相关性腹膜炎频发的相关危险因素,为降低腹膜炎反复发作风险提供干预思路和依据。方法选取2014—2018年锦州医科大学北部战区总医院收治的120例腹膜透析相关性腹膜炎患者,根据1年内腹膜炎发生次数分为单次组(1年内只发生1次)64例,多次组(1年内发生2次及以上)56例,分析腹膜炎频发危险因素。结果单因素分析显示,多次组的平均血红蛋白、血清白蛋白、钙离子浓度及首次发生腹膜炎时透析龄低于单次组,差异有统计学意义(P<0.05)。将单因素分析中有意义的因素作为自变量代入多因素logistics回归模式中,结果显示血红蛋白水平低和首次腹膜炎透析龄低是腹膜透析相关性腹膜炎频发的独立危险因素,差异有统计学意义(P<0.05)。结论血红蛋白水平低和首次发生腹膜炎时透析龄低是腹膜炎频发的独立危险因素。

Objective To explore the risk factors of frequent occurrence of peritoneal dialysis-related peritonitis,and to provide intervention strategies and evidence for reducing the risk of frequent occurrence of peritonitis.Methods Totally 120 patients with peritoneal dialysis-related peritonitis were selected from 2014 to 2018 in the Northern War Zone General Hospital of Jinzhou Medical University.According to the frequency of peritonitis in one year,64 cases were assigned into single group(only once in a year)and 56 cases were assigned into multiple group(twice or more in a year).The risk factors of frequent peritonitis were analyzed.Results Univariate analysis showed that the average hemoglobin,serum albumin,calcium concentration and dialysis age at first peritonitis in the multiple group were lower than those in the single group(P<0.05).Significant factors in univariate analysis were used as independent variables in multivariate logistic regression model.The results showed that low hemoglobin level(OR=0.971,P=0.037)and low dialysis age at first peritonitis(OR=0.970,P=0.045)were independent risk factors of frequent peritonitis.Conclusions Low hemoglobin level and low dialysis age at first peritonitis were independent risk factors for frequent peritonitis.