穿戴模拟重力服对微重力环境下人腰椎间盘退变影响

Effects of Gravity Loading Countermeasure Garment on Degeneration of Lumbar Intervertebral Disc in Microgravity Environment

目的分析微重力环境下穿戴模拟重力服对人腰椎间盘的生物力学影响。方法基于健康成年志愿者CT影像,建立人L4~5脊柱有限元模型。在腰椎有限元模型空载荷以及加载4 h 400 N轴向载荷基础上,分别模拟微重力环境下无干预和穿戴模拟重力服对腰椎间盘的生物力学影响。结果微重力环境下,人腰椎间盘中心孔压、径向位移和含水量随时间推移而增大。微重力环境穿戴模拟重力服情况下,72 h后腰椎间盘中心孔压、轴向应力、径向位移和含水量与无干预组相比均有减小。结论微重力环境下,穿戴模拟重力服了在一定程度上可帮助宇航员对抗微重力造成的对脊柱的不利影响。

Objective To analyze the biomechanical effects of gravity loading countermeasure garment on human lumbar intervertebral disc in microgravity environment.Methods Based on CT images of a healthy adult volunteer,the finite element model of L4-5 vertebrae was established.Through the empty load and 400 N axial loading for 4 hours on lumbar finite element model,the biomechanical effect of the non-intervention and gravity loading countermeasure garment were simulated respectively in microgravity environment.Results The central pore pressure,radial displacement and water content of the human lumbar intervertebral disc increased with time in microgravity environment.In the case of wearing gravity loading countermeasure garment,the central pore pressure,axial stress,radial displacement and water content of the lumbar intervertebral disc were reduced after72 hours of cyclic loading compared with the non-intervention group.Conclusions Wearing gravity loading countermeasure garment can help astronauts to prevent the adverse effects of microgravity on the spine to some extent in microgravity environment.