针刺影响细胞程序性死亡治疗缺血性脑卒中的研究进展

Research progress of the impacts of acupuncture on programmed cell death in treatment of ischemic stroke

细胞程序性死亡(自噬、凋亡、焦亡、程序性细胞坏死和铁死亡)在缺血性脑卒中病理机制中的研究取得了新的进展。针刺作为一种重要的非药物疗法广泛应用于脑卒中患者的治疗。近年研究显示,针刺可以通过调控神经细胞自噬、凋亡、焦亡、程序性细胞坏死和铁死亡途径对缺血性脑卒中发挥神经保护作用,本文对相关的研究进展进行综述。

The new progress has been made in the research of programmed cell death(e.g.autophagy,apoptosis,pyroptosis,necroptosis and ferroptosis)for the pathological mechanism of ischemic stroke.As an important non-pharmacological therapy,acupuncture is widely used in stroke patients and has achieved favorable effect.The researches in recent years have shown that acupuncture plays its neuroprotective role on ischemic stroke by modulation of autophagy,apoptosis,pyroptosis,necroptosis and ferroptosis of neurons.Acupuncture is effective in treatment of ischemic stroke by regulating programmed cell death.