血液检验指标在无症状心肌缺血患者诊断中的价值

Diagnostic value of blood test indexes in patients with silent myocardial ischemia

目的:探讨血液检验指标在无症状心肌缺血(SMI)患者诊断中的价值。方法:选取2018-03—2019-03接受治疗的80例SMI患者作为观察组,其中Ⅰ型24例、Ⅱ型30例、Ⅲ型26例。另选取同期健康体检者80例作为对照组。检测所有入组对象的血液指标:同型半胱氨酸(Hcy)、肌酸激酶同工酶(CK-MB)、心肌肌钙蛋白I(cTnI)、血小板计数(PLT)、血小板体积(PCT)、平均血小板体积(MPV)、血小板分布宽度(PDW)、红细胞分布宽度(RDW),观察2组之间的差异,分析Ⅰ型、Ⅱ型、Ⅲ型的血液检验指标变化情况,并采用皮尔逊相关系数分析法,分析各项血液检验指标与SMI的相关性。结果:观察组的Hcy、CK-MB、cTnI、RDW指标均高于对照组,差异有统计学意义(P<0.05);但2组的PLT、PCT、MPV、PDW指标比较,差异无统计学意义(P>0.05);分析其指标在Ⅰ型、Ⅱ型、Ⅲ型中的情况,Ⅰ型、Ⅱ型及Ⅲ型患者血清中的Hcy、CK-MB、cTnI、RDW依从升高,差异有统计学意义(P<0.05);血清中的Hcy、CK-MB、cTnI及RDW血液指标均与SMI呈正相关(P<0.05)。结论:SMI患者的血液指标与病理发生、发展有着密切关系,可作为SMI患者病情的诊断依据,在一定程度上,可提示患者的病情严重程度。

Objective:To explore the diagnostic value of blood test indexes in the patients with silent myocardial ischemia(SMI).Method:Eighty SMI patients treated in our hospital from March 2018 to March 2019 were selected as observation group,of which 24 were type I,30 were type II and 26 were type III.Another 80 healthy persons were selected as control group during the same period.Blood indices of all subjects were measured:homocysteine(Hcy),creatine kinase isozyme(CK-MB),cardiac troponin I(cTnI),platelet count(PLT),platelet volume(PCT),mean platelet volume(MPV),platelet distribution width(PDW)and red blood cell distribution width(RDW).The differences between the two groups were observed,and the types I,II and III were analyzed.The changes of blood test indicators were analyzed by Pearson correlation coefficient analysis,and the correlation between blood test indicators and SMI was analyzed.Result:The indexes of Hcy,CK-MB,cTnI and RDW in the observation group were higher than those in the control group,with statistical significance(P<0.05);but there was no statistical difference in the indexes of PLT,PCT,MPV and PDW between the two groups(P>0.05);the situation of the indexes in type I,type II and type III was analyzed,and the compliance of serum Hcy,CK-MB,cTnI and RDW of the patients with type I,type II and type III increased,with statistical significance.Serum Hcy,CK-MB,cTnI and RDW were positively correlated with SMI(P<0.05).Conclusion:The blood indexes of SMI patients were closely related to the development of pathology,which could be used as a diagnostic basis for the condition of SMI patients and,to a certain extent,could indicate the severity of the disease.