高脂血症发病机制及药物治疗

The pathogenesis and drug therapy of hyperlipidemia

高脂血症是一种脂质代谢异常引起的慢性疾病,与心血管疾病的发生紧密相关。随着经济快速增长、人们生活水平的提高,高脂血症发病率逐年增加。本文对高脂血症的相关研究进行总结,阐述了高脂血症的发病情况,遗传因素、营养因素、全身性疾病及肠道菌群对高脂血症的影响机制,西药的治疗特点、机制以及中医药对高脂血症的干预治疗作用,以期为相关研究提供参考。

Hyperlipidemia is a chronic disease caused by abnormal lipid metabolism,which is closely related to the development of cardiovascular disease.With the rapid economic growth and improvement of people′s living conditions,the incidence of hyperlipidemia has been increasing year by year.In this work,we summarized the research findings concerning hyperlipidemia,and described the morbidity of hyperlipidemia,the affecting mechanisms of genetic factors,nutritional aspects,systemic diseases and intestinal flora on hyperlipidemia,the therapeutic characteristics and mechanisms of Western medicine and the interventional treatment effects of Chinese medicine on hyperlipidemia,so as to provide a reference for related investigations.