重型乙型肝炎并发肺部感染患者相关危险因素及其干预措施探讨

Related Risk Factors and Intervention Measures of Patients with Severe Hepatitis B Complicated by Pulmonary Infection

目的探讨重型乙型肝炎并发肺部感染患者相关危险因素及其干预措施。方法选取2017年1月至2019年12月就诊于我院的148例重型乙型肝炎患者为研究对象,统计并发肺部感染情况,分析重型乙型肝炎并发肺部感染影响因素。结果148例重型乙型肝炎患者中合并肺部感染30例(20.27%);Logistic回归分析显示:年龄≥60岁、肝硬化失代偿期、住院时间≥3周、上消化道出血、合并糖尿病、使用抗菌药物不合理、侵入性操作、血清白蛋白<28 g/L是影响重型乙型肝炎并发肺部感染的独立危险因素(P<0.05且OR值>1)。结论重型乙型肝炎并发肺部感染是多种因素共同作用结果,临床治疗过程中需加以重视,并给予针对性的防治措施,以改善患者预后。

Objective To explore the related risk factors and intervention measures of patients with severe hepatitis B complicated by pulmonary infection.Methods A total of 148 patients with severe hepatitis B who were admitted to our hospital from January 2017 to December 2019 were selected as the research subjects.The concurrent pulmonary infection was counted,and the influencing factors of severe hepatitis B complicated with pulmonary infection were analyzed.Results Of the 148 patients with severe hepatitis B,30(20.27%)had pulmonary infection;Logistic regression analysis showed:age≥60 years,cirrhosis decompensation period,hospital stay≥3 weeks,upper gastrointestinal bleeding,and diabetes 2.Unreasonable use of antibacterial drugs,invasive operation,serum albumin<28 g/L are independent risk factors that affect severe hepatitis B complicated with lung infection(P<0.05 and OR value>1).Conclusion Severe hepatitis B complicated by pulmonary infection is the result of a variety of factors.It should be paid attention to during clinical treatment,and targeted prevention measures should be given to improve the prognosis of patients.