不同止痛药物治疗输尿管结石并肾绞痛疗效观察

Observation on the curative effect of different analgesics in the treatment of ureteral calculi with renal colic

目的对比观察不同止痛药物治疗输尿管结石合并肾绞痛的疗效。方法回顾性分析2020年3月至2022年11月青岛滨海学院附属医院急诊科收治的157例输尿管结石合并肾绞痛患者的临床资料,按照用药不同,分为4组:A组采用酮咯酸氨丁三醇注射液+消旋山莨菪碱注射液治疗;B组采用地佐辛注射液+消旋山莨菪碱注射液治疗;C组采用哌替啶注射液+消旋山莨菪碱注射液治疗;D组采用间苯三酚注射液+消旋山莨菪碱注射液组治疗。观察各组患者疼痛缓解情况,疼痛缓解时间,不良反应发生率等情况。结果A组、B组、C组的疼痛评分改善情况优于D组,D组止痛药物起效时间较其他各组更长,A组和D组不良反应发生率低于B组和C组,差异均有统计学意义(均P<0.05)。结论酮咯酸氨丁三醇注射液和消旋山莨菪碱注射液组合治疗输尿管结石合并肾绞痛止痛效果好,起效时间短,不良反应发生率低。

Objective To investigate the efficacy of different analgesics in the treatment of ureteral calculi with renal colic.Methods The clinical data of 157 patients with ureteral calculi complicated by renal colic admitted to the from March 2020 to November 2022 were retrospectively analyzed.According to the different drugs used,they were divided into 4 groups.Group A was given ketorolac tromethamine injection plus racemized anisodamine injection;group B was given diazos in injection plus racemized anisodamine injection;group C was given pethidine injection plus racemized anisodamine injection;group D was given phloroglucinol injection plus racemized anisodamine injection.The pain relief,pain relief time,and the incidence of adverse reactions in each group were observed.Results The pain score improvement in groups A,B,and C was better than that in group D;the onset time of analgesics in group D was longer than that in other groups;the incidence of adverse reactions in groups A and D was lower than that in groups B and C.All differences were statistically significant(all P<0.05).Conclusion The combination of ketorolac tromethamine injection and racemized anisodamine injection in the treatment of ureteral calculi with renal colic has a good analgesic effect,a short onset time,and a low incidence of adverse reactions.