排石汤在输尿管结石湿热蕴结型患者术后的应用效果

Effect of Paishi Decoction(排石汤)on Postoperative Patients with Ureteral Calculi of Damp-Heat Accumulation Type

目的探讨排石汤在输尿管结石湿热蕴结型患者术后的应用效果。方法选择2015年1月—2019年12月于该院接受治疗的150例输尿管结石湿热蕴结型患者展开研究,通过随机数字表法分为观察组和对照组,每组75例。对照组体外冲击波碎石术(ESWL)术后给予盐酸坦洛新缓释片治疗,观察组在对照组基础上联合排石汤治疗,均连续用药14 d。比较两组治疗效果、视觉模拟评分法(VAS)评分、肾绞痛发生率,并比较手术前后血清尿素氮(BUN)、血肌酐(Scr)水平、尿液代谢的变化及不良反应发生率。结果观察组结石排出时间、血尿消失时间均明显短于对照组,结石排净率明显比对照组高,差异有统计学意义(P<0.05);观察组术后14 d时VAS评分、肾绞痛发生率均明显低于对照组,差异有统计学意义(P<0.05);观察组术后3 d、14 d时,血清BUN、Scr水平均明显低于对照组,术后3 d时尿草酸、尿酸、尿钙水平均明显低于对照组,差异有统计学意义(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论排石汤在输尿管结石湿热蕴结型患者ESWL术后应用效果明显,可有效缓解术后疼痛,改善肾功能及尿液代谢水平,值得应用推广。

Objective To investigate the effect of Paishi Decoction(排石汤)on postoperative patients with ureteral calculi of damp-heat accumulation type.Methods A total of 150 cases of ureteral calculi with damp-heat accumulation from January 2015 to December 2019 were selected for the study.They were randomly divided into observation group and control group,75 cases in each group.The control group was treated with Tamsulosin Hydrochloride Sustained-Release Tablet after extracorporeal shock wave lithotripsy(ESWL),and the observation group was combined with Paishi Decoction on the basis of the control group.The treatment lasted for 14 consecutive days.The treatment effect,visual analogue scale(VAS)score and the incidence of renal colic were compared between the two groups,and the serum levels of urea nitrogen(BUN)and serum creatinine(Scr),urine metabolism and incidence of adverse reactions were compared.Results The stone discharge time and hematuria disappearance time in the observation group were significantly shorter than those of the control group,and the stone clearance rate was significantly higher than that of the control group,with statistically significant(P<0.05).The VAS score 14 days after operation and the incidence of renal colic in the observation group were significantly lower than those of the control group,with statistically significant(P<0.05).The serum levels of BUN and Scr in the observation group were significantly lower than those of the control group 3 and 14 days after operation,and the levels of urinary oxalic acid,uric acid and urinary calciumat 3 days after operation were significantly lower than those of the control group,with statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Paishi Decoction in ureteral calculi of damp-heat accumulation type of patients after ESWL has obvious effect and can effectively relieve postoperative pain,improve renal function and urine metabolism levels,worthy of application and promotion.