某精神专科医院特发于童年的情绪障碍门诊处方分析

Analysis of outpatient prescriptions for mood disorders in childhood in a psychiatric hospital

目的分析门诊特发于童年的情绪障碍患者的处方用药,促进临床合理用药。方法对2020年门诊全年特发于童年的情绪障碍患者的处方进行筛选、清理,最终选取处方2588张。采用回顾性研究方法分析患者处方用药的合理性、发病趋势和处方用药特点。结果收集门诊特发于童年的情绪障碍患者1107人,男性499人,女性608人,性别比1∶1.21;处方2588张,不合理处方40张,占比1.55%,以不适宜处方为主。单一用药处方1388张,占比53.63%,在抗抑郁药单一用药和联合用药中,青少年组联合用药处方率大于童年组(49.63%vs 40.29%,P<0.05);在联合用药处方占比中,女性组抗抑郁药物联合心境稳定剂和非典型抗精神病药比例大于男性组(20.65%vs 15.36%,P<0.05)。结论门诊特发于童年的情绪障碍处方用药总体性合理,女性的患病率明显高于男性,青少年患者联合用药呈增长趋势,女性患者联合用药处方占比显著大于男性,部分处方不合理,儿童青少年用药的合理性仍需关注。

AIM To analyze the prescription drugs of mood disorder patients especially in childhood in outpatient department,and promote rational drug use in clinic.METHODS The prescriptions of patients with childhood mood disorders in the outpatient department in 2020 were collected for screening and clearing.Finally,2588 prescriptions were selected to conduct a retrospective study on the rationality of patients'prescription drugs and the performance of different forms of prescription drugs in different ages and genders were analyzed.RESULTS A total of 1107 patients with emotional disorders especially in childhood were collected,including 499 males and 608 females,with a sex ratio of 1:1.21.There were 2588 prescriptions,including 40 irrational prescriptions,accounting for 1.55%,and most of them were unsuitable prescriptions.There were 1388 single drug prescriptions,accounting for 53.63%.Among single drug use and combined drug use,the rate of combined drug prescription in the adolescent group was higher than that in the childhood group(49.63%vs 40.29%,P<0.05).The ratio of antidepressants combined with mood stabilizers and atypical antipsychotics in female group was higher than that in male group(20.65%vs 15.36%,P<0.05).CONCLUSION The overall prescription drug use for mood disorders especially in childhood in outpatient department is reasonable,and the prevalence rate of female patients is significantly higher than that of male patients.Combined drug use in adolescent patients shows an increasing trend,and the proportion of combined drug prescriptions in female patients is significantly higher than that in male patients.Some prescriptions are unreasonable.The rationality of drug use in children and adolescents still needs attention.