关注糖尿病与血管钙化的共同发病机制和临床意义

Focus on the common pathogenesis and clinical significance of diabetes mellitus and vascular calcification

血管钙化(VC)广泛存在于糖尿病(DM)患者中,是DM血管病变过程中的特征性改变,也是临床不良心血管事件发生风险增加的独立危险因素。目前,VC在DM患者中的形成机制仍未完全阐明。深入探索两者间共同发病机制及内在关联,有望为预防DM心血管并发症提供新的思路。本文将对DM与VC的共同发病机制作一综述,为DM与VC的进一步研究以及临床防治提供思路。

Vascular calcification(VC)is widespread in patients with diabetes mellitus(DM),and it is a characteristic change in the process of diabetic vascular lesions.VC is also an independent risk factor for increased risk of clinical adverse cardiovascular events.At present,the mechanism of VC formation in patients with DM has not been fully elucidated.Further exploration of the common pathogenesis and internal relationship between them is expected to provide new ideas for the prevention of cardiovascular complications in patients with DM.pathogenesis of DM and VC,and provide ideas for further research and clinical prevention and treatment of DM and VC.