合成生物技术使用者潜在行为风险研究——基于计划行为理论框架

本文采用计划行为理论框架(TPB),对合成生物技术“设计构建测试学习”(DBTL)迭代路径中使用者潜在风险行为进行分析,从主观态度、主观规范、知觉行为控制和客观外部条件四个方面加以阐释,分析“意图行为”发生过程中的关键风险点。研究表明,对于DBTL的迭代研究路径中,设计和构建阶段中技术使用者的行为意图对于误用滥用行为具有正向的影响,学习阶段由于机器学习的不确定性影响机制尚不明晰。设计、构建、测试、学习四个阶段分别存在着不同的客观条件包括实验室管理、技术易获得性等对误用滥用行为有正向的影响。该研究将促进合成生物技术使用者群体行为自律、构建行为风险防控体系提供借鉴,为保障国家生物技术研究开发使用的健康行为规范提供新视角。

In this study,the theoretical framework of Planned Behavior Theory(TPB)is used to analyze the user's potential risk behavior in the iterative path“Design-Build-Test-Learn”(DBTL)of synthetic biotechnology,and the key risk factors in the process of“intention to behavior”are analyzed from four aspects:Attitude,Subjective Norms,Perceived Behavior Control and Objective Conditions.The research shows that in the iterative research path of DBTL,the intention of technology users in the Design and Build stage has a positive impact On misuse behavior,and the influence mechanism in the learning phase is not clear due to the uncertainty of machine learning.There are different objective conditions in the four stages of Design,Build,Test and Learn,including laboratory management and technology accessibility,which have a positive impact on misuse behavior.This study promotes the self-discipline behavior of users,provides reference for the construction of behavior risk prevention and control system,and presents a new perspective for the protection of healthy behavior norms used in national biotechnology research and development.