1例结肠癌晚期患者化疗联合靶向治疗的药学监护

Pharmaceutical Care for One Advanced Colon Cancer Patient Treated with Chemotherapy and Target Therapy

目的:探讨结肠癌晚期患者化疗联合靶向治疗的方案及药学监护,促进药物合理应用。方法:以1例结肠癌晚期患者的诊治过程为例,针对化疗药物及靶向药物的选择、不良反应的处理等进行药学监护。结果:患者应用FOLFIRI方案联合贝伐珠单抗治疗,治疗过程中出现窦性心动过缓、腹泻等不良反应,通过药师的药学监护,及时发现并解决了患者药物治疗中的问题,为临床用药提供了建议。结论:临床药师对肿瘤患者进行药学监护,有利于安全、合理用药。

Objective:To discuss the pharmaceutical care of patients with advanced colon cancer treated with chemotherapy and target therapy.Methods:The pharmaceutical care on a colon cancer patient treated with chemotherapy and target therapy was implemented and explored.We focused on the selection of chemotherapy and target drugs,and the monitoring of adverse reactions.Results:The patient underwent the chemotherapy of FOLFIRI and combined with bevacizumab.During the therapy,the patient had adverse reactions as diarrhea and sinus bradycardia.Through the pharmaceutical care,we discovered and solved the clinical problem on time,and provide the pharmaceutical reference for the rational use of medicines.Conclusion:The approaches for clinical pharmacists participating in pharmaceutical care on patients with colon cancer can improve therapeutic efifcacy and safety.