复方鲜竹沥液联合异丙托溴铵对慢阻肺急性加重期患者症状积分及肺功能的影响

Effect of Compound Xianzhuli Liquid Combined with Ipratropium Bromide on Symptom Score and Lung Function in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

目的分析复方鲜竹沥液联合异丙托溴铵对慢阻肺急性加重期患者症状积分及肺功能的影响.方法选取2019年1月—2020年10月该院收治的80例慢阻肺急性加重期患者为研究对象,按数字奇偶法分为两组.将采用异丙托溴铵等常规治疗的40例患者作为对照组,将在此基础上采用复方鲜竹沥液治疗的40例患者作为观察组.比较两组的治疗效果及治疗前后的中医证候积分、肺功能与血清炎症因子水平.结果比较两组的治疗总有效率,观察组的95.00%高于对照组的75.00%,差异有统计学意义(P<0.05).观察组治疗后的各项中医证候评分及各项炎症因子水平均低于对照组,各项肺功能指标均高于对照组,组间差异有统计学意义(P<0.05).结论复方鲜竹沥液联合异丙托溴铵可提高慢阻肺急性加重期患者的治疗效果,减轻临床症状,改善患者肺功能,降低炎性因子水平,临床意义较高.

Objective To analyze the effects of Compound Xianzhuli Liquid combined with ipratropium bromide on symptom score and lung function in patients with acute exacerbation of chronic obstructive pulmonary disease.Methods A total of 80 patients with acute exacerbation of COPD in this hospital from January 2019 to October 2020 were selected as the research objects and were divided into two groups according to the parity method.40 patients treated with ipratropium bromide and other conventional treatments were taken as the control group,and 40 patients treated with Compound Xianzhuli Liquid were taken as the observation group.The therapeutic effect,TCM syndrome scores,lung function and serum inflammatory factor levels before and after treatment were compared between the two groups.Results Compared the total effective rate of the two groups,the observation group's 95.00%was higher than the control group's 75.00%,the difference was statistically significant(P<0.05).After treatment,the scores of TCM syndromes and levels of inflammatory factors in the observation group were lower than those in the control group,and the lung function indexes were higher than those in the control group,the differences between the groups were statistically significant(P<0.05).Conclusion Compound Xianzhuli Liquid combined with ipratropium bromide can improve the therapeutic effect of patients with acute exacerbation of chronic obstructive pulmonary disease,alleviate clinical symptoms,improve lung function and reduce the level of inflammatory factors,with high clinical significance.