60例噻托溴铵治疗慢性阻塞性肺疾病患者的临床观察

Clinical Observation on 60 Cases of Tiotropium Bromide in the Treatment of Patients with Chronic Obstructive Pulmonary Disease

目的:探析噻托溴铵治疗慢性阻塞性肺疾病的效果。方法将60例慢性阻塞性肺疾病患者随机分为实验组和对照组两组,每组30例。两组治疗疗程均为3个月,其中,对照组的治疗方法为口服氨茶碱,试验组则采用噻托溴铵粉吸入剂进行吸入治疗。观察指标为治疗前后6min步行的距离及肺功能的指标。结果3个月的治疗后,实验组治疗前后自身的6MWD、FEV1、FEV1%、FEV1/FVC指标比较以及两组治疗后的各指标比较,其差异均有高度统计学意义(即是说<0.01),而对照组数据指标对比则显示无统计学意义(即是说>0.05)。结论采用噻托溴铵进行吸入治疗法可以明显改善慢性阻塞性肺疾病患者的肺功能和6MWD。

Objective To analysis of Tiotropium Bromide in chronic obstructive pulmonary disease.Methods 60 cases of chronic obstructive pulmonary disease were randomly divided into experimental group and control group two groups,each group of 30 people.The course of treatment of two groups for 3 months,the control group,treatment method for oral aminophyl ine,test group were treated with tiotropium bromide powder for inhalation therapy.Observed for the distance and pulmonary function before and after treatment in the six minute walk index.Results After three months of treatment,compared with their 6MWD,FEV1,FEV1%,FEV1/FVC index and the index of two groups after treatment experimental group before and after treatment,the dif erence had statistical significance(<0.01),while the contrast group data showed no statistical significance(>0.05).Conclusion The use of tiotropium bromide inhalation therapy can significantly improve lung function and 6MWD in patients with chronic obstructive pulmonary disease.