摘要
在离体大鼠心肌细胞和人工生物膜脂质体上,CoQ_(10)显著抑制氧自由基发生系统(FeCl_2,抗坏血酸)所引起的脂质过氧化物丙二醛增加,其抑制作用呈剂量依赖和时间依赖关系。本结果证实CoQ_(10)具有抗氧化作用,在膜水平上直接起到自由基清除剂样作用。
In the isolated adult rat's ventricular myocytes and artificial bio-membrane-liposomes, the lipid peroxidation caused by generating system of free radicals (FeCl2 & ascorbic acid ) was significantly inhibited by Co Q10, and the inhibition effect of Co Q10 was both dose-and time-dependent. The results showed that Co Q10 had an antioxi-dation effect and served as a scavenger of free radicals at the level of membrane .
出处
《中国药理学通报》
CAS
CSCD
北大核心
1989年第5期-,共3页
Chinese Pharmacological Bulletin
基金
国家"七五"攻关资助项目
