利多卡因雾化吸入对哮喘急性发作疗效的临床观察

A Clinical Investigation of Treatment of Acute Bronchial Asthma with Lidocaine Nebulization

目的探讨利多卡因雾化吸入对哮喘急性发作的疗效。方法采用随机、安慰剂对照方法,将80例轻、中、重度哮喘急性发作患者分为试验组(40例)和对照组(40例),对照组按常规给予吸氧、静脉滴注氨茶碱、地塞米松、抗生素治疗,试验组在常规治疗基础上加用2%利多卡因50mg超声雾化吸入。记录两组患者哮喘症状15min、30min、1h的变化。结果对照组40例中显效6例,占15%;有效24例,占60%;无效10例,占25%。试验组40例中显效24例,占60%;有效14例,占35%;无效2例,占5%。两组比较差异有显著性(P<0.05)。结论在常规应用吸氧、氨茶碱、地塞米松、抗生素治疗的基础上联合应用利多卡因雾化吸入可显著提高哮喘急性发作的疗效。

Objective To observe the treatment effects of acute bronchial asthma with lidocaine. Method 80 patients of mild, moderate and serious degree, were divided into 2 groups, experimental group and controlled group. Control group was treated with oxygen inhaling, Anchajian, dexamethasone and antibiotic, inhaled 2% lidocaine nebulization solution additional as experimental group. Symptoms of two groups were recorded in 15 minutes,30 minutes and 1 hour after the treatment. Result Of 40 cases in controlled group,16...