围手术期部分肠内营养对胃癌病人术后营养状况及免疫功能的影响

Influence of partial enteral nutrition during the perioperative period on nutritional status and immunologic function in postoperative patients with gastric cancer

目的:研究围手术期部分EN支持对胃癌病人术后营养状况、免疫功能及炎性反应的影响。方法:将60例胃癌病人随机分为围手术期部分EN组(研究组)和术后早期部分性EN组(对照组),分别按不同治疗方案进行营养支持至手术后第7天。所有病人均于术前、术后第1、8天测量体质量、皮皱厚度、上臂围、血白细胞计数、血小板、清蛋白、前清蛋白,C反应蛋白、IgG、IgM、IgA、CD4、CD8、CD4/CD8、IL-6、肿瘤坏死因子-α(TNF-α)等。结果:研究组前清蛋白和IgG水平高于对照组,IL-6低于对照组。结论:对胃癌病人进行围手术期部分EN支持,不仅能更好地改善病人术后的营养状况和免疫功能,而且还能减轻病人手术创伤后的机体炎性反应。

Objectives:To evaluate the role of the partial enteral nutrition during the perioperative period on nutritional status and immunologic function in patients with gastric cancer.Methods:Sixty patients with gastric cancer were randomized to receive either a perioperative partial enteral nutrition(study group) or an early postoperative partial enteral nutrition(control group).The weight,thickness of rhicnosis,upperarm circumference,WBC,PLT,ALB,prealbumin,CRP,IgG,IgM,IgA,CD4, CD8,CD4/CD8,IL-6,TNF-α were detected...