我国乙肝病毒垂直传播及其预防的研究现状

Status of research in vertical transmission of HBV and the Prevention.

我国是乙肝病毒的高流行区,携带者多来自垂直传播。亲代所携带的HBV可通过母婴、父婴以及遗传传播等方式感染胎儿,并于出生后造成慢性感染或病毒携带状态。目前我国采用孕期母亲注射乙肝免疫球蛋白、生后联合免疫以及母亲主动免疫等手段有效的阻断了乙型肝炎病毒的垂直传播。

Abstract; There is a high mobility of Hepatitis B virus(HBV) in China. The carrier get HBV mainly from verticaltransmission. The neonates can be infected of HBV from paren-tal generation by matermal - fetal, paternal - fetal and hereditarytransmission, and become chronic infection of HBV carrier afterbirth. Nowdays, HBV vertical transmission can be prevented bymany methods, such as intravenous immunoglobulin(IVIG) topregnant women, vaccination in infant combined with IVIG