大黄促进人体小肠溶菌酶分泌的临床研究

Correlation between rhubarb and the secretion of lysozyme in small intestine of human

目的观察大黄对肠道溶菌酶分泌的影响。方法将80个患有胃肠道肿瘤的病人随机分为两组,实验组给患者在术前2d晚间1次,术前1d早,晚各1次共3次,每次口服10%大黄液100mL,对照组相应服用饮用水。所有患者均应在距曲氏韧带80～100cm的范围内用肠钳限制10cm长度的肠段用细针穿刺肠管注入生理盐水10mL,轻揉肠管后回收液体。立即冷冻保存。分别测定两组溶液中溶菌酶的含量。结果大黄口服灌洗液中的溶菌酶的含量与饮用水相比明显增高(P<0.01)。两者之间的差异有统计学意义。结论大黄促进人体小肠溶菌酶的分泌,这是大黄保护、增强肠道黏膜的作用机制之一。

[Objective] To separate Lysozyme from small intestine of human and observe the effect of Rhubarb on the secretion of Lysozyme in small Intestine.[Method] 80 case were divided randomizedly into two groups:Experimental group were given with 100 mL 10% Rhubarb decoction two day before operation;In Control group,normal water instead of Rhubarb decoction.All cases,injected salt-water 10 mL and callback in the intestine at the 80~100 cm form treize ligament..Lysozyme activity and content were assayed by Bacterici...