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血清EB病毒特异性DNA酶抗体与鼻咽癌分期的关系 被引量:2

Relationship between serum Epstein-Barr virus-specific DNase antibody and clinical stages of nasopharyngeal carcinoma
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摘要 目的 :探讨血清非洲淋巴细胞瘤病毒特异性 DNA酶 ( Epstein-Barr virus-specific deoxynuclease,EBV-DNase)抗体与鼻咽癌 ( nasopharyngeal carcinoma,NPC)分期的关系。方法 :用 Western Blot法检测 2 64例 NPC血清 ,按“92分期法”对所有血清进行分期 ,分别计算各 T、N、M期及临床病期的 EBV-DNase抗体阳性率并进行统计学处理。 结果 :NPC各 T、N、M组及临床分期组血清 EBV-DNase抗体阳性率均无显著差异 ( P>0 .0 5 )。 结论 :早期 ( 期 ) NPC血清 EBV-DNase抗体阳性率与 ~ 期血清无明显差异 ,EBV-DNase抗体有可能成为 Objectives: To evaluate the relationship between serum EBV-DNase antibody and clinical stages of NPC. Methods: EBV-DNase antibody was detected by Western Blot in two hundred and sixty-four NPC serum categorized by TNM stages and stage groupings according to Fuzhou 92 classification system. The positive rates of EBV-DNase antibody of different TNM stages and stage groupings were analyzed statistically.  Results: The differences of serum EBV-DNase antibody positive rates between various TNM stages and stage groupings were statistically insignificant (P>0.05). Conclusions: Positive rate of Serum EBV-DNase antibody in early stages NPC was as high as those of other stages. Therefore, EBV-DNase antibody maybe a marker for the early diagnosis of NPC.
出处 《医学研究生学报》 CAS 2000年第4期221-223,共3页 Journal of Medical Postgraduates
关键词 鼻咽肿瘤 EB病毒特异性DNA酶抗体 WESTERN BLOT法 诊断 Nasopharyngeal neoplasm, carcinoma; Epstein-Barr virus-specific-DNase;  Western Blot; Diagnosis
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参考文献8

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共引文献139

同被引文献11

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