消旋卡多曲治疗婴幼儿急性腹泻34例疗效观察

EFFECTS OF RACECADOTRIL ON ACUTE DIARRHEA OF INFANTS

目的:观察消旋卡多曲口腔崩解片治疗婴幼儿急性腹泻的疗效及安全性。方法:对我院2006年10月至2007年2月收治的64例腹泻患儿,随机分成观察组和对照组,对照组予蒙脱石散、妈咪爱、补液等综合治疗,观察组为在此基础上加用消旋卡多曲口腔崩解片治疗,观察治疗期间两组患儿排便次数、脱水纠正时间等。结果:观察组总有效率94.1%,显著高于对照组66.7%(p(0.01)。结论:消旋卡多曲治疗婴幼儿急性腹泻病,可明显减少患儿大便次数、迅速纠正脱水,明显缩短病程,疗效显著,且未发现与药物有关的不良反应,安全性好。

OBJECTIVE:To observe effect and security of racecadotril orally disintegrating tablets tablets on diarrhea in infants.METHOD:64 infants with acute diarrhea who were hospitalized he from October 2006 to February 2007 were divided randomly into observation group and control group.The infants in control group accepted comprehensive treatment with Dictachedral Smectite Powder,Medilac-Vita and fluid replacement and so on.Based on the treatment,the observation group were added racecadotril orally disintegrating tablets.The changes of urination frequency and time of dehydration improvement of infants in two groups were evaluated.RESULTS:The total effective rate of observation group was 94.1%,significantly higher than 66.7% in control group(p<0.01).CONCLUSION:Racecadotril can significantly reduce urination frequency,rapidly improve dehydration and significantly shorten the course of disease.The curative effect of racecadotril orally disintegrating tablets for acute diarrhea in infants is significant,and the adverse effect of racecadotril in infants has not been not found,and the medicine is quite safe.