摘要
目的研究丹红注射液治疗慢性肾功能衰竭(CRF)氮质血症期的疗效及可能机制。方法选择CRF氮质血症期住院患者20例,在艾西特治疗的基础上,治疗组加用丹红注射液,对照组不用丹红注射液,检测两组患者治疗前后血浆ET-1含量以及血肌酐(Scr)浓度。结果治疗后,治疗组血浆ET-1、Scr浓度下降较对照组有显著性差异。结论丹红注射液可通过减少内皮细胞ET-1的产生,改善肾脏血循环,对肾功能起保护作用。
Objective To investigate the effects of Danhong on plasma ET-1 and serum creatinine(Scr) of chronic renal failure.Methods The patients with chronic renal failure were randomly assigned to Danhong treatment group and control group(without using Danhong). Plasma ET-1,Scr were measured before and after the treatment.Results Danhong can decrease Scr and plasma ET-1. Conclusion Danhong has protective effect on renal function by reducing ET-1.
出处
《中国现代药物应用》
2007年第1期19-20,共2页
Chinese Journal of Modern Drug Application
