疏血通治疗急性脑梗死疗效的Meta分析

Meta-analysis of Comparative Study on Shuxuetong Injection in the Treatment of Acute Cerebral Infarction

[目的]探讨疏血通与其他药物治疗急性脑梗死的疗效差异。[方法]收集国内杂志公开发表的文献,并运用Meta分析对临床疗效和血液流变学指标变化进行同质性检验和合并效应量估计。[结果]疏血通的临床疗效和对照组有显著性差异(P<0.01),前着明显优于后者。血液流变学指标中全血高切黏度、血浆比黏度、纤维蛋白原的改善,疏血通组和对照组有显著性差异;全血低切黏度比较两者没有显著性差异。[结论]疏血通组治疗急性脑梗死的疗效是确切,较其他常用的药物疗效更明确。

[Objective]To study the difference of efficacy of Shuxuetong injection from other medicine in the treatment of acute cerebral infarction.[Methods]27 comparative studies of Shuxuetong and other medicine in the treatment of acute cerebral infarction were analyzed by meta-ananlysis about antidepressants indicators.[Results]The clinical efficacy of Shuxuetong was obviously superior to that in control group.The hemorheology indicators(the whole blood viscosity in high shear rates,whole blood viscosity,fibrinogen change)of Shuxuetong were obviously superior to that in control group,but the whole blood viscosity in low Shuxuetong had no significant difference from control group.[Conclusion]Shuxuetong has positive effect on the treatment of acute cerebral infarction compared with other medicine.