超声造影在移植肾急性排斥中的应用

Application of contrast-enhanced ultrasound in transplanted kidney with acute rejection

目的探讨移植肾急性排斥患者超声造影特征,为建立移植肾急性排斥反应的超声造影诊断标准提供依据。方法选择2007年9月至2010年7月期间就诊于南京军区福州总医院超声诊断科的同种异体移植肾患者99例,均知情同意。其中移植肾肾功能稳定者58例,移植肾术后时间为(43.48±42.68)d;移植肾急性排斥患者41例,急性排斥发生的时间为移植术后(41.91±54.21)d。所有患者常规超声检查结束后进行超声造影,观察并记录各相关参数。结果 41例移植肾急性排斥患者与58例移植肾肾功能稳定患者相比,超声造影时肾实质内造影剂充填始终较功能正常移植肾稀疏,包膜下皮质未能完全呈强回声充填,髓质内见散在的、大小不等、边界不清的低灌注区,整个移植肾切面始终未能显示"火球样"图像。超声造影各参数中皮质、髓质的上升时间、达峰时间均延长(P<0.05)。结论移植肾发生急性排斥反应时,超声造影显影效果、时间-强度曲线质量均不同程度降低,造影剂灌注时间、排空时间较肾功能稳定者延长。

Objective To discuss the imaging features of contrast-enhanced ultrasound after acute rejection in transplanted kidney,and provide information for a diagnosis standard of the acute rejection in transplanted kidney.Methods Ninetynine transplanted patients in Department of Ultrasound Diagnosis,Fuzhou General Hospital,were chosen from September 2007 to July 2010.They were informed and agreed to join the study.Of all,there were 58 cases with stable function,the time after renal transplantation was 43.48±42.68 d...