摘要
对中药藤黄中的藤黄酸的提取分离进行了方法改进.通过渗漉、吡啶成盐、三次重结晶、置换萃取等步骤得到橙黄色藤黄酸单体.藤黄酸得率为23.9%.并通过IR、MS、1HNMR、13CNMR对藤黄酸进行了结构鉴定.
The studies were opitimized the extraction process of gambogic acid from traditional chinese medicine gamboge resin.Gambogic acid was isolated in overall yield of approximately 23.9% from the easily and widely available gamboge resin.It was purified by converting the Percoaltion extract from the gamboge resin into pyridine salt,and then three times recrystallization in methanol,followed by displacing with hydrochloric acid and extracting with ether.The structure of gambogic acid was confirmed by IR,1HNMR,13CNMR and MS.
出处
《辽宁大学学报（自然科学版）》
CAS
2011年第2期97-99,共3页
Journal of Liaoning University：Natural Sciences Edition
基金
国家重大新药创制项目(20092X09103-030)
关键词
藤黄
藤黄酸
提取分离
结构鉴定
Gamboge resin
Gambogic acid
Extraction
Structural identification
