直肠癌同时性肝转移的外科治疗

Surgical treatment of rectal cancer with synchronous hepatic metastases

目的探讨直肠癌同时性肝转移外科治疗手术时机及方法。方法对2006年8月至2008年8月在我中心32例直肠癌同时性肝转移患者的诊断和治疗的临床资料进行回顾性分析。结果术前B超、CT、MRI能够明确诊断直肠癌肝转移灶能否手术切除;术前新辅助化疗及靶向治疗可以进一步筛选直肠癌肝转移;治疗模式是以手术为主的综合性治疗。结论可切除的直肠癌肝转移首选手术治疗;采取合适的、个体化综合治疗手段能够提高无瘤生存率和累计生存率。

Objective To investigate the surgical occasion and approach of rectal cancer with synchronous hepatic metastases.Methods Retrospective analysis was conducted on the clinical data of 32 patients who had been diagnosed as rectal cancer with synchronous hepatic metastases.Results The resectability of hepatic metastasis site from rectal cancer for the patient could be exactly diagnosed by type-B ultrasonic,computer tomography(CT) and magnetic resonance imaging(MRI) before surgical operation.Neo-adjuvant chemotherapy and targeted therapy would aid a lot in the further filter of patients who had been diagnosed as rectal cancer with synchronous hepatic metastases.Comprehensive therapy which mainly based on surgical was adopted.Conclusion Surgical treatment was still the first choice for the patients with resectable rectal cancer with synchronous hepatic metastases.Appropriate subject-specific comprehensive therapy could improve the disease free survival rate and accumulated survival rate.