期刊文献+

FOLFOX方案治疗晚期胃癌的临床效果分析

下载PDF
导出
摘要 目的探讨高剂量氟脲嘧啶、亚叶酸钙与草酸铂(FOLFOX方案)方案在晚期胃癌治疗中的应用效果。方法选取该院2009年12月—2011年12月期间收治的晚期胃癌患者61例,2周为1周期的化疗,并采用FOLFOX方案,在第1、2天行200mg/(m2·d)CF静滴2h,在第1天行400mg/(m2·d)5-FU静推,第1、2天行1600mg/(m2·d)5-FU静滴22h,第1天行130mg/(m2·d)L-OHP静脉输注4h,在4周期后间隔1个月进行疗效评定。结果疗程结束后,对于38例初治病患的有效率为50.0%,23例复治病患的有效率为43.5%。结论对于晚期胃癌患者的治疗,每两周行高剂量的FOLFOX方案安全且有效。
出处 《中国卫生产业》 2012年第28期98-99,共2页 China Health Industry
  • 相关文献

参考文献3

二级参考文献20

  • 1谭爱荣.乐沙定联合亚叶酸钙及5-氟尿嘧啶治疗晚期胃癌的临床观察[J].实用癌症杂志,2006,21(1):72-73. 被引量:14
  • 2金懋林.进展期胃癌全身化学治疗研究新进展[J].癌症进展,2007,5(1):18-24. 被引量:82
  • 3Louvet C,Andre T,Tigaud JM,et al.Phase II study of oxaliplatin,fluo-rouracil and folinic acid in locally advanced or metastatic gastric cancer patients.J Clin Oncol,2002,20(23):4543-4548.
  • 4Artru P,Andre T,Tigaud JM,et al.Oxaliplatin(OXA),5-Fluo-rouracil,and Folinic acid(FA)in advanced metastatic gastric carcinoma(AMGC)patients:final results of a multicenter phase II study.Pro Am Soc Clin Oncol,2001,20:165.
  • 5Yeon HP,Jae LL,Beak YR,et al.Capecitabin in combination with Oxaliplatin(XELOX)as a first-line therapy for advanced gastric cancer.Cancer Chemother Pharmacol,2008,61:623-629.
  • 6Chao ying Liu,Qing Sun,Xiaosheng Hang,et al.Multicenter phase Ⅱ study of Capecitabin plus Oxaliplatin as a first-line therapy in Chinede patients with advanced gastric cancer.Anti-Cancer Drugs,2008,19:825-831.
  • 7Van Cursem E. The treatment of advanced gastric cancer: new findings on the activity of the taxanes [J]. Oncologist, 2004,9 ( Suppl 2) :9.
  • 8De Gramont A, Figcer A, Sceymour M, et al. Leucororin and fluorouracil with or without oxalipatin as first-line treatment in advanced colorectal cancer [ J ]. J Clin Oncol, 2000, 18 (16) :2938.
  • 9Park Y, Lee J, Ryoo B, et al. A phase II study of capacit abine plus oxalip latin (XELOX) as first - line therapy for patients with advanced gastric cancer[J]. Proc Am Soc Clin Oncol,2006,24 : 197S.
  • 10Kamangar F,Dores GM,Anderson WF.Patterns of Cancer Inciden-ce,Mortality,and Prevalence across Five Continents:Defining Priorities to Reduce Cancer Disparities in Different Geographic Regions of the World[J].J Clin Oncol,2006,24(14):2137-50.

共引文献24

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部