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Autoimmune polyglandular syndrome type 3 complicated by mineralocorticoid-responsive hyponatremia of the elderly 被引量:2

Autoimmune polyglandular syndrome type 3 complicated by mineralocorticoid-responsive hyponatremia of the elderly
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摘要 We experienced the first case with autoimmune polyglandular syndrome type 3(anti-thyroid peroxidase ant ib ody-positive hypothyroidism and anti-glutamic acid decar boxylase antibody-positive diabetes) complicated by miner alocorticoid-responsive hyponatremia of the elderly.This case is also a rare slowly progressive insulin-dependent diabetes mellitus(SPIDDM) case,for which the patient has been treated for many years with sulfonylurea or glinide.Our observation also demonstrated that glucose metabolism in autoimmune diabetes such as SPIDDM is influenced by appetite,thyroid function and glucocorticoid effect. We experienced the first case with autoimmune polyglandular syndrome type 3 (anti-thyroid peroxidase antibody-positive hypothyroidism and anti-glutamic acid decarboxylase antibody-positive diabetes) complicated by mineralocorticoid-responsive hyponatremia of the elderly. This case is also a rare slowly progressive insulin-dependent diabetes mellitus (SPIDDM) case, for which the patient has been treated for many years with sulfonylurea or glinide. Our observation also demonstrated that glucose metabolism in autoimmune diabetes such as SPIDDM is influenced by appetite, thyroid function and glucocorticoid effect.
出处 《World Journal of Diabetes》 SCIE CAS 2010年第4期135-136,共2页 世界糖尿病杂志(英文版)(电子版)
关键词 Anti-glutamic acid DECARBOXYLASE antibody AUTOIMMUNE polyglandular syndrome Mineralocorticoidresponsive HYPONATREMIA of the elderly Slowly progressive INSULIN-DEPENDENT diabetes MELLITUS Anti-glutamic acid decarboxylase antibody Autoimmune polyglandular syndrome Mineralocorticoid-responsive hyponatremia of the elderly Slowly progressive insulin-dependent diabetes mellitus
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  • 1Kobayashi,T,Tamemoto,K,Nakanishi,K,Kato,N,Okubo,M,Kajio,H,Sugimoto,T,Murase,T,Kosaka,K.Immunogenetic and clinical characterization of slowly progressive IDDM[].Diabetes Care.1993
  • 2S Ishikawa,T Saito,A Fukagawa,M Higashiyama,T Nakamura,I Kusaka.Close association of urinary excretion of Aquaporin-2 with appropriate and inappropriate arginine vasopressin-dependent antidiuresis in hyponatremia in elderly subjects[].The Journal of Clinical Endocrinology.2001
  • 3Neufeld,M,Maclaren,N,Blizzard,R.Autoimmune polyglandular syndromes[].Pediatric Annals.1980
  • 4Zimmet P,Turner R,McCarty D,et al.Crucial points at diagnosis: Type 2 diabetes or slow type 1 diabetes[].Diabetes Care.1999

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