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老年肺癌患者血清P53抗体、VEGF、TGF-β1水平 被引量:3

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摘要 目的探讨老年肺癌患者血清P53抗体、血管内皮生长因子(VEGF)、转化生长因子(TGF)-β1水平对肺癌诊断的价值。方法采用酶联免疫吸附(ELISA)法检测肺癌患者血清P53抗体、VEGF、TGF-β1水平。结果老年肺癌患者血清P53抗体(17.84±8.73)ng/L、VEGF(416.7±162.8)ng/L、TGF-β1(68.74±17.91)ng/L水平分别比正常对照组(5.43±1.90)ng/L、(34.3±12.4)ng/L、(20.44±6.58)ng/L显著升高(均P<0.001)。老年肺癌患者血清P53抗体水平、VEGF水平、TGF-β1水平与肿瘤大小、淋巴转移、远端转移、TNM分期有关。结论老年肺癌患者血清P53抗体、VEGF、TGF-β1水平明显高于正常对照组,测定血清P53抗体、VEGF、TGF-β1水平对肺癌的早期诊断、分期、治疗和预后可提供重要的临床依据。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2014年第12期3283-3285,共3页 Chinese Journal of Gerontology
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