新生儿呼吸窘迫综合征高危因素的多变量Logistic回归分析

Multivariate logistic regression analysis of the risk factors of respiratory distress syndrome in neonates

目的:对新生儿呼吸窘迫综合征(RDS)进行流行病学调查,分析其高危因素。方法:2011年2月一2013年1月间调查10 104个新生儿,包括监护病房收治的122例RDS患儿。应用Logistic回归分析计算优势此(OR)及其95%置信区间。结果:胎龄<32周,新生儿性别,低出生体重,产妇年龄,选择性剖宫产是RDS的高危因素;而产妇妊娠期疾病不能作为RDS独立的危险因素。结论:新生儿出现RDS及预后受多种因素影响。应防止新生儿出现RDS的各种高危因素,采取措施有效降低新生儿RDS的发生率,并改善患儿预后。

Objective:To investigate the risk factors of respiratory distress syndrome(RDS) in neonates via an epidemiologic survey.Methods:A total of 10104 neonates,including 122 neonates with RDS in the intensive care unit,were surveyed between February 2011 and January 2013.Multivariate regression analyses,including the odds ratios and 95%confidence intervals,of the risk factors of RDS were performed.Results:The gestational age of 32 weeks or less,gender,low birth weight,maternal age,caesarean section,but not the maternal diseases during pregnancy,were risk factors of RDS in neonates.Conclusion:The incidence and prognosis of RDS could be influenced by multiple factors.This warrants effective measures to reduce the incidence of neonatal RDS and improve the prognosis.