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Axon guidance and neuronal migration research in China 被引量:8

Axon guidance and neuronal migration research in China
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摘要 Proper migration of neuronal somas and axonal growth cones to designated locations in the developing brain is essential for the assembly of functional neuronal circuits.Rapid progress in research of axon guidance and neuronal migration has been made in the last twenty years.Chinese researchers began their exploration in this field ten years ago and have made significant contributions in clarifying the signal transduction of axon guidance and neuronal migration.Several unique experimental approaches,including the migration assay of single isolated neurons in response to locally delivered guidance cues,have been developed by Chinese neuroscientists to investigate the molecular machinery underlying these guidance events. Proper migration of neuronal somas and axonal growth cones to designated locations in the developing brain is essential for the assembly of functional neuronal circuits.Rapid progress in research of axon guidance and neuronal migration has been made in the last twenty years.Chinese researchers began their exploration in this field ten years ago and have made significant contributions in clarifying the signal transduction of axon guidance and neuronal migration.Several unique experimental approaches,including the migration assay of single isolated neurons in response to locally delivered guidance cues,have been developed by Chinese neuroscientists to investigate the molecular machinery underlying these guidance events.
出处 《Science China(Life Sciences)》 SCIE CAS 2010年第3期304-314,共11页 中国科学(生命科学英文版)
基金 supported by the Innovation Project of the Chinese Academy of Sciences (Grant No KSCX2-YW-R-103) National Natural Science Foundation of China (Grant No 30625023) the National Basic Research Program of China (Grant Nos 2006CB806600 and 2006CB943903)
关键词 AXON GUIDANCE NEURONAL MIGRATION development NEURONAL CIRCUITS axon guidance neuronal migration development neuronal circuits
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