再发性腹痛儿童幽门螺杆菌IgG测定及分析

Analysis of HP-IgG in children with recurrent abdominal pain

目的 探讨儿童再发性腹痛 (RAP)与幽门螺杆菌 (HP)感染的关系。方法 采用酶联免疫吸附法检测血清中相应的HP -IgG抗体。 结果 2 662例再发性腹痛儿童 ,HP -IgG阳性者 789例 ,检出率 2 9 64 %;男女性别感染率无显著性差异 ,P >0 0 5。结论 ①再发性腹痛儿童HP感染状况不容忽视 ;②血清学方法可作为HP感染初步筛选试验 ,根据其结果再进行1 3 C尿素呼气试验 ( 1 3 C -UBT)判断HP感染状态。两种试验方法结合诊断HP感染具有创伤小、准确、快速。

Objective To investigate the relation between patients with recurrent abdominal pain and Helicobacter pylori (Hp)infection Methods Serum HP-IgG antibody was detected with ELISA Results Of the 2 662 children investigated,789 patients were HP-IgG positive The positive rate was 29 64% There was no significant difference in sex ratio of the infection( P >0 05) Conclusion ①HP infection in children is common ②Serological test is a good method for mass screening 13 C-UBT can be then performed for the patients with positive result to confirm active HP infection