农药对喷洒员血常规及生化指标的影响

Effect of pesticides on farm sprayers' blood routine test and biochemistry indexes

目的 :探讨农药喷洒对喷洒员血常规及生化的影响。方法 :选取 2周内喷洒农药的10 0名农药喷洒员为接触组 ,10 0名当地同期门诊健康体检者为对照组。对两组人员进行问诊、体格检查 ,空腹抽静脉血作肝功能 (TP、TB、AL T、AST、AL P、GGT、Ch E) ,肾功能 (Cr、BUN、UA)及血常规(Hb、WBC、PL T)检测。结果 :接触组有急性轻度中毒的临床表现 ,以皮肤、眼部刺激症状最为明显 ,其次为消化系统和神经系统症状。两组人群肝、肾功能及血常规检测结果的均值在正常范围内 ,但接触组多项指标的均值与对照组比较差异有显著性。其中肝功能 :TB、AL T、AST、AL P高于对照组 ,Ch E低于对照组 ,差异有显著性 (P<0 .0 5 ,P<0 .0 1) ;肾功能 :BUN、U A高于对照组 ,差异有显著性 (P<0 .0 1) ;血常规 :PL T、Hb低于对照组 ,差异有显著性 (P<0 .0 5 ,P<0 .0 1)。结论 :农药喷洒对喷洒员的肝、肾功能及血常规会产生一定影响 ,需加强对农药喷洒员的健康监测。

Objective:To study effects of pesticides on farm sprayers’ blood routine test and biochemistry indexs. Methods:100 farm sprayers spraying pesticides in 2 weeks were elected as exposed group, 100 residents as control group. Physical examinations, blood routine test [hemoglobin (Hb), white blood cell (WBC), platelet (PLT)] and biochemistry {liver function [total proteins (TP), total bilirubin (TB), alanine transaminase (ALT), aspartic transaminase (AST), alkaline phosphatase (ALP), choline esterase (ChE)], renal function [creatinine (Cr),uric acid (UA), blood urea nitrogen (BUN)] were examed in 100 farm sprayers and 100 controls. Result: The levels of blood routine test in exposed group were lower than those in control group Hb( P <0.05),PLT ( P <0.01), WBC ( P >0.05). The levels of biochemistry in exposed group were higher than those in control group TB( P <0.05),ALT AST ALP BUN UA( P <0.01),TP Cr ( P >0.05). The level of ChE in exposed group was lower than those in control group( P <0.01). The number of abnormal indexes in exposed group were higher than those in control group( P <0.01). Conclusion :Spraying pesticides affected farm sprayers’ blood routine test and biochemistry indexes. The health surveillance of farm sprayers should be more strengthened.