摘要
利用电子顺磁共振(EPR)方法直接观察二甲基亚砜(DMSO)在碱性有氧条件下产生超氧阴离子自由基(O·_2)的反应过程,以此反应为产生O·_2^-的模型体系,加入党参、黄芪、当归、赤芍等几味传统的延缓衰老天然药物,研究其对O·_2信号的增强或抑制效应。结果表明,这些天然药物对O·_2有很强的清除作用。
The superoxide anion radical (Of) produced in the alkaline dimethyl sulfoxide (DMSO) system was directly measured by electron paramagnetic resonance (EPR) at low temperature. This reaction was used as a model system for generating O2-. Astragalus membranaceus, Codonopsis pilousla, Paeonia laetiflora, Angelica sincnsis and Sophora flavescens, traditional natural medicines which have the effect of delaying anility, were added into the model system to observe their intensifying or inhibiting effect on EPR signals of O2. These results suggest that these traditional natural medicines have the mostly eliminating effect on Of produced in the alkaline DMSO system.
出处
《第二军医大学学报》
CAS
CSCD
北大核心
1993年第1期48-50,共3页
Academic Journal of Second Military Medical University
关键词
电子顺磁共振
自由基
天然药物
electron paramagnetic resonance
superoxide
radical
natural medicine