摘要
目的:观察电刺激小脑顶核(fastigialnucleus,FN)结合康复训练治疗急性脑梗死的疗效。方法:入选急性期颈内动脉系统脑梗死患者139例,随机分为3组,治疗组49例,接受FN电刺激结合康复治疗;康复组46例,单纯康复治疗;对照组44例,单纯药物治疗,所有患者其他治疗按神经内科常规。在治疗前和治疗后8周分别进行美国国立卫生研究院卒中量表(NIHSS)、简式Fugl-Meyer评分(FMA)、Barthel指数(MBI)评定以观察疗效。结果:治疗前3组患者各项功能评分之间差异无显著性意义(P>0.05),治疗后:NIHSS,治疗组为3.53±3.28,康复组为4.67±4.14,对照组为5.73±4.54,组间比较差异有显著性意义(F=4.323,P=0.016);FMA和MBI评分治疗后治疗组和康复组均优对照组,而且治疗组优于康复组(P<0.05)。结论:电刺激小脑顶核结合康复训练能够有效改善急性脑卒中患者的功能预后。
AIM:To observe the curative effect of electrical stimulation of cerebellar fas tigial nucleus(FN) and rehabilitation therapy in patients with acute cerebral in farction. METHODS:Totally 139 patients with acute cerebral infarction of internal caroti d artery were included in the study.All patients were assigned into three groups : treatment group(n=49,treated with electrical stimulation of FN and rehabilitat ion),rehabilitation group(n=46,treated with rehabilitation) and control group(n= 44,receiving drug treatment only).Other treatments were according to the routine of department of neurology.All the patients were evaluated with national instit utes of health stroke scale(NIHSS),Fugl-Meyer Assessment(FMA) and modified Bart hel index(MBI) before and 8 weeks after treatment. RESULTS:There were no significant differences in the scores of NIHSS, FMA and MBI among the three groups before treatment(P >0.05).After treatments, the score s of NIHSS in the treatment, rehabilitation and control groups were 3.53±3.28,4 .67±4.14 and 5.73±4.54, respectively,and there were significant differences am ong the groups(F=4.323,P=0.016);while the scores of FMA and MBI in the treatment and rehabilitation groups were both better than those in the control group(P< 0 .05). CONCLUSION:Combination of electrical stimulation of cerebellar FN and rehabili tation therapy can effectively ameliorate the functional prognosis of patients w ith acute cerebral infarction.
出处
《中国临床康复》
CSCD
2004年第22期4408-4409,共2页
Chinese Journal of Clinical Rehabilitation
