山东省沿海地区甲状腺肿患病现状及尿碘水平调查

A SURVEY OF PRESENT STATUS OF THYROID GOITER AND ITS URINE IODINE IN PATIENTS RESIDING IN THE COASTAL REGIONS OF SHANDONG PROVINCE

①目的 探讨山东沿海地区甲状腺肿的患病现状并对尿碘水平进行调查。②方法 采用随机分层整群抽样法 ,对山东沿海地区烟台、威海、日照和青岛甲状腺肿患病情况进行调查 ,并以五莲县作为对照。③结果沿海地区甲状腺肿的患病率为 9.4 9% ,明显高于五莲县 (4 .2 7% ) (u =6 .74 ,P <0 .0 1)。沿海地区甲状腺肿抗甲状腺过氧化物酶抗体 (TPOAb)、球蛋白抗体 (TGAb)和尿碘明显高于对照组 (t=2 .15～ 2 .93,P <0 .0 5、0 .0 1)。尿碘与TGAb呈正相关 (r=0 .2 4 ,P <0 .0 1)。④结论 山东沿海地区甲状腺肿和尿碘浓度有明显的区域分布 ,居民离海越近 ,甲状腺肿的患病率也越高。离海较近地区居民应适当减少高碘物质的摄入。

Objective To investigate the prevalence of thyroid goiter (TG) and the level of urine iodine in patients living in coastal regions in Shandong province. Methods The goiter was surveyed in population residing in the coastal areas of Yantai, Weihai, Rizhao and Qingdao by random stratification sampling. The mountainous county of Wulian served as the control. Results The coastal prevalence of TG was 9.49%, higher than that of Wulian (4.27%)(u=6.74,P<0.01). The iodine concentrations in concentrations in urine had positive correlation to TGAb (r=0.24,P<0.01). Conclusion The prevalence of TG in Shandong coastal regions showed regional distribution. The nearer to the coast, the higher the prevalence is. The residents in the coast should take in less food containing high iodine.