大豆多肽对辐射的保护功能

Study on radioprotective effect of bacillus subtilis

目的 研究大豆多肽的辐射保护功能。方法 以每日 0 2 1,0 4 2 ,1 2 6 g/ (kg·bw)大豆多肽胶囊灌喂小鼠 6 0d ,在第 30d给予一次性全身γ射线照射 ,观察小鼠辐照后 30d存活率、平均存活时间、白细胞总数、骨髓细胞DNA含量及血清溶血素水平。结果 大豆多肽能使辐照后小鼠 30d存活率明显增高、平均存活时间延长、白细胞总数明显增加 ,能提高骨髓细胞DNA含量和血清溶血素水平。结论 大豆多肽具有辐射保护作用。

Objective To research the radioprotective effect of bacillus subtilison 60 Co γ-ray-induced injury.Methods Mice were treated with three different doses of bacillus subtilis in 60 days.All groups were irradiated once with 60 Co γ-ray on thirtieth-day,and then the difference in survival rate,average survival time,the changes in white blood cells,quantity of DNA in marrow cell and serum hemolysin were observed.Results The 30-day survival rate,average survival time,the WBC counts ,quantity of DNA in marrow cell and serum hemolysin of Bacillus subtilis-protected mice were all much higher than those of the control group.Conclusion Bacillus subtilis had significant anti-radiation effect.