冠心病患者胸痛症状的性别差异

Sex difference in symptom of chest pain in CHD patients after an acute coronary event.

目的 了解冠心病患者急性冠脉事件后胸痛症状在性别上的分布差异。方法 连续性收录心内科急性冠脉事件 1周内冠心病患者 6 83例 ,7天之内予以标准问卷调查 ,记录临床及非临床数据 ,以及 1周内的胸痛症状及发作情况。应用单因素及多因素分析确定胸痛发作的相关因子。结果 单因素分析显示 ,女性较男性报告胸痛症状比例明显高 (90 .3%vs83.1% ,P =0 .0 16 ) ;但多因素分析显示两者并无显著性差异 ,有无胸痛症状主要与冠心病的诊断分型、患者健康自评分级、有无运动习惯及是否合并情绪焦虑有关。

Objective To explore whether there is sex difference in reporting of symptom of chest pain in CHD inpatients after an acute coronary artery event.Methods CHD inpatients within 7 days of onset of an acute coronary artery event including SAP, UAP and AMI, and those who underwent angiography and PTCA were consecutively recruited. Standardized questionnaires including whether there is a recent chest pain or not were administered within 7 days. Depression and anxiety were measured by HADS-D. χ 2 test and t test were used to compare the patients with and without chest pain. Logistic regression analysis was used to adjust for confounders.Results 396 males ( 83.1%) and 187 females ( 90.3%) reported symptom of chest pain (P= 0.016). However, after adjustment for confounders by using logistic regression analysis, chest pain was significantly associated with patients' diagnostic type of CHD, self-evaluation of health statue, exercise habit and co-morbidity of anxiety.Conclusion There is not significant difference between the male and female CHD inpatients in reporting the symptom of chest pain right after an acute coronary event.