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西藏拉萨地区藏族正常人群骨矿含量分布研究 被引量:7

Investigation on normal value of bone mineral density measured with pDEXA on people in the Tibet
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摘要 目的 为了解正常藏族人群骨量分布 ,确定峰值骨量的年龄段 ,寻找骨丢失规律 ,为骨质疏松骨密度诊断标准提供参考依据。方法 选择 5~ 89岁健康藏族男女 6 81人 ,2 0岁以前以 5岁为一年龄段 ,其它以 10岁为一年龄段 ,对男女分别进行分组。用DTX - 2 0 0 (美国OSTEOMETER公司提供 )双能X线密度仪 ,对非优势手臂的远端进行测量 ,取结果的平均值 ,数据输入SPSS软件数据库进行统计分析。结果 峰值骨量男女都在 30~ 39年龄段 ,以后随年龄增加骨量逐渐减少。男性在 6 0~ 6 9年龄段骨量丢失达 17.6 1% ,70~ 79年龄段骨量丢失达 2 3.90 % ;女性在 5 0~ 5 9年龄段 13.91%。女性 6 0~ 6 9年龄段骨量丢失已达 2 6 .4 8%。结论 应依据不同地区正常人群骨量分布 ,建立诊断标准 ,用骨量丢失百分率诊断骨质疏松具有普遍意义。 Objective To find the change regularities of BMD in the distal part of the forearm of healthy pepole with increasing age in Lasa of Tibet, provide usful data for diagnosis of osteoporosis and establish the method of prevent diagnosis with physiological age. Methods 681 healthy pepole aged 5 through 89 years in Beijing were selected to involve in the study. BMD of the subjects was measured by pDEXA(Osteometer MediTech, DTX-200 ) at the distal part of the non-dominant forearm. The data were divided into different groups by sex, age(one group span 10 years, but before 20 year one group span 5 years). All data were saved in computer and all statiscal analysis were performed using SPSS 10.0 system. Results Both male and females reached their peak bone mass at 30-39 years of age.Then, the bone mass decreased with increasing age. Compared to the peak bone mass, men in 60-69 years bone mass lost 17.61%, those in 70-79years 23.90%; women in 50-59 years bone lost 13.91%, and in 60-69 years 26.48%. Conclusions The baseline for the diagnosis of osteoporosis should be established according the measured data of healthy people in different districts .It is generaly accepted for replacing standard deviation by percentage of bone loss to diagnosis osteoporosis.
出处 《中国骨质疏松杂志》 CAS CSCD 2004年第3期299-301,共3页 Chinese Journal of Osteoporosis
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  • 1Advani S, Wimalawansa. Bones and nutrition:common sense supplementation for osteoporosis. Curr Womens Health Rep,2003,3(3) :187-192.
  • 2Albagha OM, Ralston SH. Genetic determinnatnts of susceptibility to osteoporosis. Endocrinol Metab Clin North Am,2003,32:65-81.
  • 3刘忠厚.中国骨质疏松诊断的进展[A]..第九届全国骨质疏松年会会议文集[C].成都,2003..
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