珠海市部分幼儿园儿童乙型肝炎感染情况

ANALYSIS ON INFECTION OF HEPATITIS B IN SOME KINDERGARTENS OF ZHUHAI.

目的 :了解珠海市 2～ 5岁儿童乙型肝炎感染率及免疫接种水平 ,为制定乙肝疫苗的免疫策略提供依据。方法 :2 0 0 2年 6～ 11月对珠海市幼儿园按随机抽样方法 ,对 8个公立幼儿园和 10个私立幼儿园共 185 6名 2～ 5岁儿童 ,采用酶联免疫吸附法 (EL ISA)测定 HBs Ag、抗 - HBs,现场检查儿童的免疫接种证或儿童免疫接种登记表计算接种率。结果 :HBs Ag总阳性率为 3.2 9% ,各年龄组间差异无显著性 ;抗 - HBs总阳性率 71.4 4 % ,随着年龄的增大而增高 ,各年龄儿童差异有显著性 ;公立幼儿园的 HBs Ag阳性率显著低于私立幼儿园 ,抗 - HBs阳性率、乙肝疫苗基础接种率和加强接种率公立幼儿园明显高于私立幼儿园。结论 :该市仍应加强对儿童的乙肝基础免疫工作 。

Objective:To study the infection rate and the level of vaccination of hepatitis B on children aged from two to five in Zhuhai.To provide strategy for stipulating vaccination plan.Methods:Using random cluster sampling among 8 public kindergarten and 10 private kindergarten,1856 children had been investigated.HBsAg,Anti-HBs were determined by ELISA,vaccination cards were cheched.Results:The positive rate of HBsAg is 3.29%,the rate of Anti-HBs is 71.44%,there is significant difference in age groups in public kindergarten.Conclusion:To reduce infect rate of hepatitis B in children,the most effective measure is hepatitis B vaccination for infants and it is also important to improve base and enhance vaccination to children.Vaccination for extra flow children is the emphasis in the future.