乙型肝炎转变为肝癌的长期观察

Long-term Observation of the Conversion of Hepatitis B to Hepatocarcinoma

对16例乙型肝炎病人转变为肝癌的临床特点作了长期观察。起病时的肝炎类型为急性无黄疸型3例,慢活肝5例,慢迁肝及肝硬化各4例。转变为肝癌经历最短2年5个月,有11例在10年以后癌变。巨块型肝癌8例,结节型5例,浸润型3例。年龄最小32岁,平均53岁。转变为肝癌的首发症状均为肝区痛疼及痛疼加剧。定期 B 超探查仍是确诊手段。病人转变为肝癌的过程中乙肝病毒标记始终阳性。从发现肝癌至死亡时间平均8个半月。

Long-term observation of the clinical characteristics of the conversion of hepatitis B (HB) to hepatocarcinoma (HC) was made in 16 patients.The original types of HB comprised 3 cases of acute anicterus hepatitis,5 cases of chronic active hepatitis,4 cases of chronic persistent hepatitis,and 4 liver cirrhosis.The shortest duration of conversion lasted two years and five months,and 11 other cases took more than ten years.Among the 16 HC,there were 8 cases of giant malar type,5 cases of nodular type,and 3 cases of infiltrating type.The youngest patient was only 32 years old,the mean age was 53.The onset symptom was aggravation of pain in the liver area.Regular examination with ultrasonic B is still the process to make a diagnosis.During the period of conversion to hepatocarcioma,hepatitis B virus is always positive.The average time from discovery to death is eight months and a half.