KTP激光联合药物灌注治疗泪道阻塞性疾病

KTP laser with medicine rinse for lacrimal duct occlusion

目的探讨KTP激光泪道成形术联合药物灌注治疗泪道阻塞性疾病的临床效果。方法对不同类型泪道阻塞性疾病385例(492眼),随机分为2组,Ⅰ组(275眼)激光泪道成形术后,地塞米松+庆大霉素混悬液冲洗泪道,四环素可的松眼膏+5-氟脲嘧啶注入泪道。Ⅱ组(217眼)激光泪道成形术后,地塞米松+庆大霉素混悬液冲洗泪道后,仅给予四环素可的松眼膏注入泪道。术后口服抗生素、激素及局部点抗生素、激素眼液,定期泪道冲洗。结果Ⅰ组(275眼),术后前期治愈好转率为98%,3mo后为94%;Ⅱ组(217眼),术后前期治愈好转率为96%,3mo后为92%。结论KTP激光泪道成形术联合药物灌注治疗泪道阻塞性疾病,有良好疗效,值得临床进一步推广应用。

AIM: To explore the effect of KTP laser plastic operation associated with medicine rinse in lacrimal duct occlusion. · METHODS: A total of 385 case (492 eyes) of lacrimal duct occlusion had been treated with laser plastic operation were randomly divided into two groups. Group I (275 eyes) was rinsed by the mixture of gentamycin, dexamathasone, cortisone betracycline and 5-FU; Group II (217 eyes) was rinsed by the above mixture except 5-FU.· RESULTS: In Group I, the prior-rate of cured and improved was 98%. After 3mo, the rate of cured and improved was 94%. In Group II, the prior-rate of cured and improved was 96%. After 3mo, the rate of cured and improved was 92%.· CONCLUSION: KTP laser plastic operation associated with medicine rinse is an effective method for the treatment of lacrimal duct occlusion, and it should be generalized in clinic.·