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牙周炎患者红细胞SOD血清LPO水平的变化 被引量:4

The Changes of SOD and LPO Level in Blood of Periodontitis
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摘要 对40例牙周炎患者,按肾虚标准分为肾虚组20例,无肾虚组20例,进行了二项自由基损伤的检测:采用化学发光法检测红细胞 SOD 活性,比色法检测血清 LPO 水平;并与19例口腔相对者(无牙周病、粘膜病)作对照检测。结果表明:牙周炎组 SOD 活性低于健康组,LPO 水平高于健康组。有肾虚症状的牙周炎患者SOD 活性水平低于健康组及无肾虚的牙周炎组;其 LPO 水平高于健康组及无肾虚牙周炎组。无牙周炎组与健康组比较,其 SOD,LPO 水平皆无差异。提示:牙周炎患者可因肾虚时体内自由基加剧,从而加重牙周病变。 The SOD activity in RBG and the LPO in serum were measured in forty patients with periodontitis whom ac-cording to the criteria of“kidney defficiency were divided into patients with”kidney difficiency“group and patientswithout“kidney defficiency”group,19 healthy persons were selected as the control group.Statistical analyses of the data showed:The SOD activity in patients with periodontitis was lower than control group,but the LPO level was heigherthan control group.The SOD activity in patients with“kidney defficieney”was lower than patients without“kidney defficiency”andcontrol group,but the LPO level was hegher than the patients without“kidney defficieney”and control group.There are no difference in the SOD activity and LPO level between the patients without“kidney defficiency”and control group.These results might suggest that the patients with“kidney defficieney”accumulate a lot of super oxides in thetissue,thus it increase the free radical damage of the periodontal tissue.
出处 《华西口腔医学杂志》 CAS CSCD 北大核心 1993年第1期7-9,共3页 West China Journal of Stomatology
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