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载脂蛋白E基因多态性在肾脏病领域的研究进展 被引量:4

Progress of apoE gene polymorphism in renal disease
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摘要 载脂蛋白E(apoE)在脂质代谢中起关键性调节作用 ,已经明确apoE与老年性痴呆、心血管疾病关系密切 ;同时越来越多的研究发现apoE基因多态性与许多肾病的发生、发展有关 ,特别是糖尿病肾病、脂蛋白肾小球病(LPG)。 Apolipoprotein E is an important regulation factor in lipids metabolism. It has been accepted that apolipoprotein E is relevant to many diseases such as Alzheimer′s disease and coronary heart diseases. And increasing study has revealed that apoE gene polymorphism is associated with some kidney diseases. We reviewed the progress of influences of apoE gene polymorphism on renal diseases.
作者 王军 俞雨生
出处 《医学研究生学报》 CAS 2004年第11期1019-1022,共4页 Journal of Medical Postgraduates
关键词 载脂蛋白E 基因多态性 慢性肾病 apoE Gene polymorphism Chronic kidney disease
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