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类风湿关节炎表皮生长因子及β_2微球蛋白的测定 被引量:3

Determine of Epidermal Growth Factor and β_2-Microglobulin in Patients with Rheumatoid Arthritis
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摘要 目的 探讨表皮生长因子 (EGF)与 β2 微球蛋白 ( β2 M )在类风湿关节炎 (RA)发病机理及诊断中的意义。方法 用放射免疫分析法 (RIA)测定 71例RA患者血清EGF、β2 M。结果 RA患者血清EGF、β2 M显著升高 ,说明EGF、β2 M在RA的发病中可能起一定作用 ,但与RA的活动性无关。 Objective To investigate the roles of epidermal growth factor(EGF) and β_2-microglobulin(β_2-M) in the pathogenesis and diagnosis of rheumatoid arthritis(RA).Method 71 patients with RA were observed.EGF and β_2-M in serum were measured by radioimmunoassay.Results The levels of EGF and β_2-M in serum of patients with RA were significantly higher than those of the controls.Conclusions EGF and β_2-M may play a role in the pathogenesis of RA,but they aren't related to the activity of RA.
出处 《现代诊断与治疗》 CAS 2004年第6期327-328,共2页 Modern Diagnosis and Treatment
基金 福建省福清市科技发展基金资助
关键词 RA β2—M Β2微球蛋白 类风湿关节炎 EGF 表皮生长因子 患者 活动性 Epidermal growth factor(EGF) β_2-microglobulin(β_2-M) Rheumatoid arthritis
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