摘要
利用三种实验模型研究了芒果甙的肝保护作用。三种大鼠肝损伤模型分别由醋氨酚(A-PAP),四氯化碳(CCl4)和D-氨基半乳糖(D-GalN)诱导形成。芒果甙能明显降低三种肝损伤模型大鼠血清的谷丙转氨酶(GPT)和谷草转氨酶(GOT)水平,病理检查结果显示,芒果甙并能使大鼠肝损伤显著减轻,表明其具有一定的肝保护作用。
The mangiferin was investigated on the hepatoprotective effects in three kinds of
models of experimentally-induced liver injuries in rats. The models were induced by
acetaminophen, carbon tetrachloride, and D-GalN. The results showed that mangiferin caused
significant reduction of the elevated enzyme levels of serum glutamate oxaloacetate
transminase, serum glutamate pyruvate transminase in model rats, and alleviated the
pathological damages in livers of the model rats. These findings are suggestive of the potent
hepatoprotective effects of mangiferin.
出处
《中国实验动物学杂志》
1999年第1期24-27,共4页
Chinese Journal of Laboratory Animal Science